Quantitative MRI of the Brain Measuring Changes Caused by Disease

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2003 | 652 Pages | ISBN: 0470847212 | PDF | 12 MB
(Radiology category)"This is an exciting book, with a new approach to use of the MRI scanner. It bridges the gap between clinical research and general neuro-radiological practice. It is accessible to the clinical radiologist, and yet thorough in its treatment of the underlying physics and of the science of measurement. It is likely to become a classic." British Medical AssociationThis indispensable 'how to' manual of quantitative MR is essential for anyone who wants to use the gamut of modern quantitative methods to measure the effects of neurological disease, its progression, and its response to treatment. It containsboth the methodology and clinical applications, reflecting the increasing interest in quantitative MR in studying disease and its progression. The editor is an MR scientist with an international reputation for high quality research The contributions are written jointly by MR physicists and MR clinicians, producing a practical book for both the research and medical communities A practical book for both the research and medical communities "Paul Tofts has succeeded brilliantly in capturing the essence of what needs to become the future of radiology in particular, and medicine in general - quantitative measurements of disease." Robert I. Grossman, M.D. New York, University School of Medicine (from the Foreword)Content: Chapter 1 Concepts: Measurement and MR (pages 1-15): Paul S. ToftsChapter 2 The Measurement Process: MR Data Collection and Image Analysis (pages 17-54): Paul S. ToftsChapter 3 QA: Quality Assurance, Accuracy, Precision and Phantoms (pages 55-81): Paul S. ToftsChapter 4 PD: Proton Density of Tissue Water (pages 83-109): Paul S. ToftsChapter 5 T1: The Longitudinal Relaxation Time (pages 111-141): Penny A. Gowland and Valerie L. StevensonChapter 6 T2: The Transverse Relaxation Time (pages 143-201): Philip A. Boulby and Fergus J. Rugg-GunnChapter 7 D: The Diffusion of Water (pages 203-256): Claudia A.M. Wheeler?Kingshott, Gareth J. Barker, Stefan C. A. Steens and Mark A. van BuchemChapter 8 MT: Magnetization Transfer (pages 257-298): Paul S. Tofts, Stefan C. A. Steens and Mark A. van BuchemChapter 9 Spectroscopy: 1H Metabolite Concentrations (pages 299-339): Paul S. Tofts and Adam D. WaldmanChapter 10 T1?W DCE?MRI: T1?Weighted Dynamic Contrast?Enhanced MRI (pages 341-364): Geoff J. M. Parker and Anwar R. PadhaniChapter 11 T2? and T2*?W DCE?MRI: Blood Perfusion and Volume Estimation using Bolus Tracking (pages 365-412): Richard P. Kennan and H. Rolf JagerChapter 12 Functional MRI (pages 413-453): Peter Jezzard and Nick F. RamseyChapter 13 ASL: Blood Perfusion Measurements Using Arterial Spin Labelling (pages 455-473): Laura M. Parkes and John A. DetreChapter 14 Biology: The Significance of MR Parameters in Multiple Sclerosis (pages 475-499): Bruno Brochet, Klaus G. Petry and Vincent DoussetChapter 15 Spatial Registration of Images (pages 501-531): John Ashburner and Catriona D. GoodChapter 16 Volume and Atrophy (pages 533-558): Geoff J. M. Parker and Declan T. ChardChapter 17 Shape and Texture (pages 559-579): William R. CrumChapter 18 Histograms: Measuring Subtle Diffuse Disease (pages 581-610): Paul S. Tofts, Gerard R. Davies and Jamshid DehmeshkiChapter 19 The Future of qMR: Conclusions and Speculation (pages 611-617): Paul S. Tofts


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